Work

Rapid 64Cu radiolabeling and in vivo evaluation of DSPE–NODAGA liposomes in a murine mammary tumor model

Year: 2025

Type: article

Abstract: Cu-labeled PEGylated liposomes (PL-NODAGA) and significant tumor accumulation, validating DSPE-NODAGA's potential for real-time tracking of liposome delivery. These findings establish the incorporation of DSPE-NODAGA as a robust and adaptable platform for PET-based monitoring of lipidic nanomedicine.

Source: Pharmacological Research

DOI: 10.1016/j.phrs.2025.108065

Authors: Elena Markova, Mathias Kranz, Morten Karlsen, Camilla Wolowczyk, Angel Moldes-Anaya, Nataša Škalko-Basnet, Rune Sundset, Alexandros Marios Sofias, Rodrigo Berzaghi, Montserrat Martin-Armas, Sjoerd Hak

Institutions: UiT The Arctic University of Norway, St Olav's University Hospital, Norwegian University of Science and Technology, University Hospital of North Norway, Universitätsklinikum Aachen, RWTH Aachen University, SINTEF Industry

Language: English

Topic: Radiopharmaceutical Chemistry and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,130

Funders: Tromsø Forskningsstiftelse, Norges Forskningsråd

OpenAlex ID: W4417279644

FWCI: 0.545

Cites: 66

Cited by: 1

Related to: