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Latex-Contaminated Kidney Graft as a Source of Perioperative Anaphylaxis: A Case Report

Year: 2025

Type: article

Abstract: Introduction: Latex allergy is a leading cause of perioperative anaphylaxis, yet the risk of graft-mediated exposure during solid organ transplantation is poorly characterised. Case Presentation: We report the case of a 45-year-old man with end-stage renal disease and confirmed latex allergy who underwent kidney transplantation with a graft that had been handled with latex gloves during procurement. Following multidisciplinary discussion, the graft was repeatedly rinsed with preservation solution to reduce antigenic load. The operating theatre was prepared as latex-free, and the anaesthesia team implemented enhanced readiness for anaphylaxis. The surgery and perioperative course were uneventful, and the patient was extubated in theatre and transferred to intensive care without complication. Conclusion: This case underscores the potential for graft-mediated anaphylaxis due to latex contamination during procurement. Systematic latex avoidance from organ retrieval to implantation, along with communication between procurement and implant teams, is crucial to mitigate risk in sensitised recipients.

Source: Case Reports in Nephrology and Dialysis

DOI: 10.1159/000549587

Authors: Elodie Faure, Mane Andreassian, Ahmad Mroue, Ophélie Le Monnier, Benoit Plaud, Benjamin Deniau