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Novel Protein Tyrosine Phosphatase Nonreceptor Type 2 (PTPN2) Inhibitors for Cancer Treatment

Year: 2025

Type: article

Abstract: Protein tyrosine phosphatase nonreceptor type 2 (PTPN2) is an enzyme that plays a critical role in regulating cell growth, development, and survival. This patent showcases the synthesis and pharmaceutical compositions of novel PTPN2 inhibitors and their applications in the prevention, treatment, and amelioration of cancers.

Source: ACS Medicinal Chemistry Letters

DOI: 10.1021/acsmedchemlett.5c00692

Authors: Xin Zhou, Steven H. Liang

Institution: Emory University

Language: English

Topic: Protein Tyrosine Phosphatases

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4417284140

FWCI:

Cites: 3

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