Year: 2025
Type: article
Study design: Case Report
Abstract: Raynaud's phenomenon is a vasospastic disorder that may occur as a primary benign condition or as a secondary manifestation of systemic disease. We describe the case of a 63-year-old man, with stage IV squamous cell carcinoma of the left lung undergoing palliative chemotherapy, who developed asymmetric and transient discoloration of the distal upper extremities. The patient's clinical history of active cancer, combined with exclusion of other secondary causes, supported a paraneoplastic etiology. Paraneoplastic Raynaud's phenomenon should be considered in adults with atypical or new-onset vasospastic symptoms, especially in the context of established malignancy. Early recognition is essential to optimize symptom management and enhance understanding of paraneoplastic vascular syndromes associated with lung cancer.
Source: Cureus
DOI: 10.7759/cureus.99075
Authors: Beatriz Vitó Madureira, Rita Aranha, Rita Soares Costa
Institution: Unidade Local de Saúde de Entre Douro e Vouga
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4417291313