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Borrelia afzelii Hepatitis in Patient Treated with Venetoclax and Obinutuzumab, Switzerland

Year: 2025

Type: article

Abstract: We report Borrelia afzelii hepatitis in an immunosuppressed patient in Switzerland receiving anti-CD20 therapy and venetoclax. Diagnosis was made by metagenomic sequencing and PCR. This case underscores the need to consider Lyme borreliosis in unexplained hepatitis cases and highlights the value of molecular diagnostics in immunosuppressed patients when serologic test results are negative.

Source: Emerging infectious diseases

DOI: 10.3201/eid3111.250584

Authors: Gioele Capoferri, Raphael Battegay, Baptiste Hamelin, Peter M. Keller, Kirsten D. Mertz, Maja Weisser

Language: English

Topic: Vector-borne infectious diseases

Subfield: Parasitology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4417297373

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