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Non‐Invasive and Rapid Quantitative Elasticity Analysis of Seborrheic Keratosis Based on Optical Coherence Elastography: An Exploratory Study

Year: 2025
Type: article
Abstract: Seborrheic keratosis is a common benign skin tumor. None of the current conventional testing techniques can assess the mechanical properties of the tissue, such as hardness, elasticity and viscoelasticity. In this study, we investigated the morphological and elastic properties of seborrheic keratosis (SK), a common benign skin tumor, using optical coherence elastography (OCE). We found that the OCE technique was able to distinguish SK tissue from normal tissue. In addition, by measuring skin elasticity, it was possible to identify SK lesions with different clinical types and dermoscopic patterns of presentation. As a non-invasive quantitative tool, OCE demonstrates significant potential in the clinical diagnosis and assessment of skin aging diseases, providing objective evaluations based on elasticity.
DOI: 10.1002/jbio.202500513
Authors: Shiyang Li, Yawen Guo, Ting Meng, Jiahui Luo, Xiao Han, Yangyang Gong, Wenmin Fei, Xianwei Cao
Institutions: Nanchang University, Jiangxi Provincial Academy of Medical Sciences, First Affiliated Hospital of Jiangxi Medical College, First Affiliated Hospital of Nanchang University, Tianjin University, Nanchang Hangkong University, Beihang University
Language: English
Open Access status: bronze
OpenAlex ID: W4417313981
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Cites: 34
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