Year: 2025
Type: article
Abstract: Upstream processes strongly influence downstream analysis in sequential data-processing workflows, particularly in machine learning, where data quality directly affects model performance. Conventional statistical imputations often fail to capture nonlinear dependencies, while deep learning approaches typically lack uncertainty quantification. We introduce a hybrid imputation model that integrates a deep learning autoencoder with Convolutional Neural Network (CNN) layers and a Transformer-based contextual modeling architecture to address systematic variation across heterogeneous data sources. Performing multiple imputations in the autoencoder–transformer latent space and averaging representations provides implicit batch correction that suppresses context-specific remains without explicit batch identifiers. We performed experiments on datasets in which 10% of missing data was artificially introduced by completely random missing data (MCAR) and non-random missing data (MNAR) mechanisms. They demonstrated practical performance, jointly ranking first among the imputation methods evaluated. This imputation technique reduced the root mean square error (RMSE) by 50% compared to denoising autoencoders (DAE) and by 46% compared to iterative imputation (MICE). Performance was comparable for adversarial models (GAIN) and attention-based models (MIDA), and both provided interpretable uncertainty estimates (CV = 0.08–0.15). Validation on datasets from multiple sources confirmed the robustness of the technique: notably, on a forensic dataset from multiple laboratories, our imputation technique achieved a practical improvement over GAIN (0.146 vs. 0.189 RMSE), highlighting its effectiveness in mitigating batch effects.
Source: Big Data and Cognitive Computing
DOI: 10.3390/bdcc9120321
Institution: Sidi Mohamed Ben Abdellah University
Language: English
Subfield: Statistics and Probability
Field: Mathematics
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $2,172
OpenAlex ID: W4417317650