Accelerating UF/DF of nucleic acids with real-time monitoring and automated process control
Year: 2025
Type: article
Abstract: The implementation of variable pathlength spectroscopy in ultrafiltration and diafiltration processes addresses critical limitations in nucleic acid manufacturing through real-time concentration monitoring and automated process control. This article presents real-world case studies demonstrating significant time savings and achieving less than 5% deviation from target concentration endpoints through integrated tangential flow filtration systems.
Source: Nucleic Acid Insights
Author: Nigel Herbert
Institution: Repligen (United States)
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W4417318379
FWCI:
Cites:
Cited by:
Related to: