Work

Subacute sclerosing panencephalitis

Year: 2025

Type: article

Abstract: Subacute sclerosing panencephalitis (SSPE) is a rare, fatal complication of measles, manifesting years after infection due to persistent measles virus in the central nervous system. An 11-year-old Syrian boy with prior measles and measles - mumps - rubella (MMR) vaccination developed progressive encephalopathy and a vegetative state. MRI showed diffuse white matter, thalamic, and pontine changes; SSPE was confirmed post-mortem. This case emphasises the need for high MMR vaccine coverage and the importance of clinical awareness of rare infectious diseases in patients from crisis-affected countries.

Source: Ugeskrift for Læger

DOI: 10.61409/v03250235

Authors: Anna Bryan Stensbøl, Kristina Træholt Franck, Zohra Fatima Umar, Malene Landbo Børresen

Institutions: Copenhagen University Hospital, Rigshospitalet, Statens Serum Institut, Sjællands Universitetshospital, Nykøbing F.

Language: Danish

Topic: Virology and Viral Diseases

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4417320519