Maximizing CAR-T cell yields: scalable solutions with perfusion and stirred-tank bioreactors
Year: 2025
Type: article
Abstract: The primary drivers impacting cell and gene therapy (CGT) time-to-market and COGs include productivity, enabling process control, and ensuring the quality of the final cell product. Achieving these goals requires a functional supply chain and the ability to seamlessly scale-up. This article will discuss the collaborative study between Satorius and University College London, exploring process intensification strategies in stirred-tank bioreactors for CAR-T manufacturing.
Source: Cell and Gene Therapy Insights
Institutions: Sartorius (Germany), University College London
Language: English
Topic: CAR-T cell therapy research
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4417331959
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