Anesthetic Management of a Pediatric Patient with Rubinstein–Taybi Syndrome Undergoing Entropion Correction Surgery: A Case Report
Year: 2025
Type: article
Study design: Case Report
Abstract: Rubinstein–Taybi syndrome (RTS) is a rare genetic disorder that presents unique anesthetic challenges, including a high likelihood of difficult airway management and an increased risk of arrhythmias associated with certain medications. We report the anesthetic management of a 2-year-old patient with RTS undergoing entropion correction surgery. Cisatracurium was selected over rocuronium to reduce the potential for cardiovascular complications, and reversal agents were deliberately avoided due to concerns about arrhythmogenic risk. The pre-administration of lidocaine during induction and before extubation, along with continuous quantitative neuromuscular monitoring throughout the procedure, contributed to a smooth extubation and stable postoperative recovery. This case emphasizes the importance of individualized anesthetic strategies that prioritize safety and cost-effectiveness. It also highlights the critical roles of appropriate muscle relaxant selection, maintenance of hemodynamic stability, timely lidocaine administration, and the use of neuromuscular monitoring in optimizing perioperative outcomes for patients with RTS.
Source: Journal of Medical Sciences
Authors: Yu-Fan Wang, Yi-Hsiung Lu, Ke-Hung Chien, Chun-Chang Yeh
Institutions: Tri-Service General Hospital, National Defense Medical Center
Language: English
Subfield: Anesthesiology and Pain Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4417333467