Work

A unimolecular near-infrared fluorescent probe for in vivo imaging of enzymes with minimized false-negative signals

Year: 2025

Type: article

Abstract: imaging. This study not only introduces a robust unimolecular NIR fluorescent probe to mitigate false-negative diagnoses in ovarian cancer but also establishes a versatile design strategy for developing multi-enzyme-responsive imaging agents, offering a promising approach to enhance diagnostic accuracy in clinical settings.

Source: Chemical Science

DOI: 10.1039/d5sc07381b

Authors: Jinliang Han, Mingwang Yang, Chengyuan Lv, Kang Li, Jiangli Fan, Xiaojun Peng

Institutions: Dalian University of Technology, State Key Laboratory of Fine Chemicals, Jinfeng Laboratory, Hubei Jiufengshan Laboratory

Language: English

Topic: Molecular Sensors and Ion Detection

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: National Natural Science Foundation of China, Department of Science and Technology of Liaoning Province, Fundamental Research Funds for the Central Universities