Optimizing bioprocess purification: effective nucleic acid removal in high salt environments
Year: 2024
Type: article
Abstract: Efficient cell lysis and host cell DNA removal are crucial in biopharmaceutical purification, especially for viral vectors. This article will discuss how an advanced salt-active endonuclease can enhance bioprocess purification workflows by effectively removing nucleic acid impurities and meeting stringent regulatory standards.
Source: Cell and Gene Therapy Insights
Authors: Eleonora Turco, Joanna Niska-Blakie
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W4417364310
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