Work

Long-term high-protein diet intake accelerates adipocyte senescence through macrophage CD38-mediated NAD+ depletion

Year: 2025

Type: article

Abstract: crosstalk as a central axis linking dietary protein excess to WAT aging, providing actionable targets for the prevention and treatment of age-related metabolic disorders.

Source: Molecular Metabolism

DOI: 10.1016/j.molmet.2025.102306

Authors: Xiaohan Yang, Lun Hua, Dengfeng Gao, Yanni Wu, Yi Yang, Xianyang Jin, Xuemei Jiang, Chao Jin, Bin Feng, Lianqiang Che, Shengyu Xu, Yan Lin, Long Jin, Yong Zhuo, Mingzhou Li, De Wu

Institution: Sichuan Agricultural University

Language: English

Topic: Sirtuins and Resveratrol in Medicine

Subfield: Geriatrics and Gerontology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,270

Funders: Innovative Research Group Project of the National Natural Science Foundation of China, National Natural Science Foundation of China, Agriculture Research System of China, China Agricultural Research System, Key Technologies Research and Development Program, National Key Research and Development Program of China, Science and Technology Plan Projects of Tibet Autonomous Region

Awards: G2001100668, G3144562759, G543546516, G5948608813, G6722235242, G7538662703, G7560749481, G935186064

OpenAlex ID: W4417427313

FWCI: 1.064

Cites: 75

Cited by: 2

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