Percutaneous Endocardial Septal Pulsed Field Ablation for Hypertrophic Obstructive Cardiomyopathy: A Case Report
Year: 2025
Type: article
Study design: Case Report
Abstract: A 53-year-old man was diagnosed with hypertrophic obstructive cardiomyopathy (HOCM). Transthoracic echocardiography (TTE) demonstrated a basal interventricular septal thickness of 13.7 mm and a left ventricular outflow tract gradient (LVOTG) of 73 mmHg. Under intracardiac echocardiography and three-dimensional electroanatomical mapping system guidance, the patient underwent percutaneous endocardial septal pulsed field ablation (PES-PFA). Clinical improvement was achieved. Invasive assessment showed the transaortic pressure gradient decreased from 59 to 32 mmHg. At 1-month follow-up, TTE confirmed LVOTG reduction to 40 mmHg. This case highlights PES-PFA as a novel approach for HOCM, though further investigation is warranted to establish its safety and efficacy.
DOI: 10.1111/pace.70103
Authors: Yanfeng Tian, Haoruo Zhang, Songqing Yang, Chenbo Chu, Haoran Jing, Chunlin Gong, Jiaoyue Zhong, Geer Sheng, Yuran Chen, Shufeng Xing, Hongkun Duan, Siting Hong, Hui Liu, Zhaojun Wang
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Funder: Harbin Medical University
OpenAlex ID: W4417429444