Surface or Luminal? Decoding Tumor Extracellular Vesicle Logic for Functional Insight and Therapeutic Reprogramming (Adv. Funct. Mater. 51/2025)
Year: 2025
Type: article
Abstract: Tumor Extracellular Vesicle Logic In their Research Article (10.1002/adfm.202521108), Chi-An Cheng and co-workers introduce a nanoscale transformation, as tumor extracellular vesicles (EVs) travel from heterogeneous danger to homogeneous cure. This cover art illustrates the journey of the EV Bimodal Functional Regulator (eBFR): CLEAR purges hidden oncogenic cargo, SWITCHER isolates surface-defined EV subtypes, and eSimoa quantifies spatial protein signatures—reprogramming tumor EVs into safe, pure, and thousands-fold drug-loaded couriers for precision medicine.
Source: Advanced Functional Materials
DOI: 10.1002/adfm.73137
Authors: Jhih‐Fong Li, Syuan‐Wei Chen, Yu‐Syuan Chu, Shih‐Tang Kuo, Ying‐Hwa Hung, Pin‐Yu Yeh, Ying‐Ai Chen, Ssu‐Pei Yu, Chun‐Jung Ko, Chi‐An Cheng
Institution: National Taiwan University
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W4417433248
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