Work

The LPA2 receptor PDZ domain affects canonical Wnt signaling in colon cancer cells

Year: 2025

Type: article

Abstract: PDZminus receptor negatively affected its ability to activate canonical Wnt signaling and unexpectedly, it also impaired the Wnt-3a ligand-induced activation of canonical Wnt signaling in colon cancer cells.

Source: Cellular Signalling

DOI: 10.1016/j.cellsig.2025.112318

Authors: M. Cristina Castañeda-Patlán, Juan Carlos Martínez- Morales, Marco Antonio Morquecho-León, Paola Briseño-Díaz, K. Helivier Solís, M. Teresa Romero-Ávila, J. Adolfo García-Sáinz, Martha Robles-Flores

Institution: Universidad Nacional Autónoma de México

Language: English

Topic: Wnt/β-catenin signaling in development and cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,550

Funders: Møre og Romsdal Fylkeskommune, Universidad Nacional Autónoma de México, Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México

OpenAlex ID: W4417435656

FWCI:

Cites: 45

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