Establishment of six human induced pluripotent stem cell lines from healthy Central Asian donors (IPBi115-A, IPBi116-A, IPBi117-A, IPBi119-A, IPBi124-A, and IPBi129-A)
Year: 2025
Type: article
Abstract: Six human induced pluripotent stem cell (iPSC) lines (IPBi115-A, IPBi116-A, IPBi117-A, IPBi119-A, IPBi124-A, and IPBi129-A) were established from peripheral blood mononuclear cells (PBMCs) of healthy donors from Kazakhstan and Uzbekistan, representing Central Asian populations. These lines retained pluripotency, differentiated into the three germ layers, and showed normal karyotypes, with confirmed Sendai virus clearance, donor-matched STR profiles, and mycoplasma-free status. These iPSC resources expand population diversity for stem cell research and provide valuable platforms for disease modeling and drug screening, supporting human-based approaches in biomedical research.
Source: Stem Cell Research
Authors: Miju Lee, Yoon-Eun Kim, Wonjue Choi, Songeun Nah, Mira Han, Chan Yeong Heo, Mahito Nakanishi, Jihwan Song
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $2,360
Funder: Ministry of Food and Drug Safety
Award: G8696436936
OpenAlex ID: W4417437651