Year: 2025
Type: article
Study design: Systematic Review
Abstract: Objective: This article systematically reviewed intervention strategies for cancer-related sarcopenia (CRS), providing evidence for researchers to develop targeted treatments. Methods: PubMed, Embase, Web of Science, and the Cochrane Library were searched for studies between 2015 and 2025, followed by literature screening and content analysis. Results: A total of 3,566 articles were initially identified, and 18 randomized controlled trials (published between 2016 and 2025; sample sizes ranging from 15 to 232) were ultimately included. CRS interventions were categorized into four types: nutritional, exercise, pharmacological, and multidisciplinary. Conclusion: A CRS intervention needs an integrated approach that combines nutrition, exercise, pharmacology, and a multidisciplinary team (MDT) to improve patients' functional outcomes and quality of life. Future research should focus on precision approaches and translational medicine.
Source: Frontiers in Nutrition
Authors: Lei Li, Haiyan Zhu, Jiangxia Chen, Lingchang Shan, Jiamin Xu
Institutions: Shaoxing University, Shaoxing People's Hospital
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,801
OpenAlex ID: W4417449036