Efficacy of Emblica Officinalis and Curcumin Longa, Two Significant Herbal Antioxidants, in the Management of OSMF: A Comparative Cross-sectional Study
Year: 2025
Type: article
Abstract: Introduction: Oral submucous fibrosis (OSMF) is a persistent, potentially cancerous condition that affects 6.42 out of every 1000 people in South Asia. It causes burning sensation, limited mouth opening, and fibrosis. This study compares the efficacy of Emblica officinalis and Curcumin longa, two potent herbal antioxidants, in managing OSMF symptoms. Materials and Methods: Sixty clinically diagnosed OSMF patients were equally divided into Groups A and B who received Emblica officinalis and Curcumin longa respectively (i.e., twice daily for 2 months). Data was analyzed using the Chi-square and Student’s paired t -test ( P < 0.05). Results: Group A showed greater reduction in oral burning (Visual Analogue Scale scores), while Group B exhibited significant improvement in mouth opening. Discussion: Curcumin longa was more effective in improving mouth opening and reducing fibrous bands, for treating OSMF-related structural and functional deficits. Emblica officinalis offered more relief from the burning sensation, indicating its importance in symptomatic therapy. Conclusion: A combination therapy may offer a more holistic approach. Future research should explore nanoparticle formulations of Curcumin longa and Emblica officinalis to enhance their therapeutic potential in OSMF and fibrosis.
Authors: Annette M. Bhambal, Parnavi Mishra, Sudhanshu Saxena, Palak Jain Choudhary, Akshay K. Agarwal, Aparna Raj
Language: English
Subfield: Periodontics
Field: Dentistry
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $250
OpenAlex ID: W4417451123