Work

Sustainable mechanochemical synthesis of functionalisable fluorinated scaffolds for drug discovery using green LAG

Year: 2025

Type: article

Abstract: Mechanochemical S N Ar has been achieved using green solvents Cyrene or water for liquid assisted grinding to prepare fluorinated drug scaffolds.

Source: RSC Mechanochemistry

DOI: 10.1039/d5mr00100e

Authors: Adam G. Buchanan, Elizabeth T. Areola, Maryam Farrukh Butt, Yan Kiu Lee, Jasper Murphy, Annie E. Taylor, Avninder S. Bhambra, George W. Weaver

Institutions: Loughborough University, De Montfort University

Language: English

Topic: Fluorine in Organic Chemistry

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Responsible consumption and production

Open Access status: diamond

Funder: De Montfort University

OpenAlex ID: W4417451197

FWCI: 0.339

Cites: 40

Cited by: 1

Related to: