Work

Extracellular vesicle–mediated microRNA signaling: expanding insights into intercellular communication and disease modulation

Year: 2025

Type: article

Abstract: Extracellular vesicles (EVs), particularly exosomes, have emerged as key mediators of intercellular communication by transporting microRNAs (miRNAs). Recent studies indicate that EV-associated miRNAs regulate gene expression across diverse physiological and pathological processes, including cancer metastasis, neuroinflammation, kidney injury, and cardiovascular disease. Understanding the selective packaging, trafficking, and functional consequences of EV-miRNA transfer may enable the development of biomarkers and targeted therapies based on vesicle-mediated signaling.

Source: Annals of Medicine and Surgery

DOI: 10.1097/ms9.0000000000004579

Authors: Syeda Tayyaba Batool, Umair Ali, Muhammad Ijaz Khan, Raghabendra Kumar Mahato

Institutions: University of Azad Jammu and Kashmir, University of Swabi, Gandaki Medical College

Language: English

Topic: Extracellular vesicles in disease

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,850