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Oncolytic HSV-1–Mediated JAG1 Blockade Induces Glioma Senescence-Associated Secretory Phenotype to Increase Macrophage Activation and Cetuximab-Mediated Senolysis

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Year: 2025
Type: article
Source: Cancer Research
DOI: 10.1158/0008-5472.can-25-1402
Authors: Kimberly A. Rivera-Caraballo, Tae Jin Lee, Arnoneel Sinha, Marco Orecchioni, Rafal Pacholczyk, Karina Vázquez-Arreguín, Shilpa Sharma, Kimya Jones, Kailash Vemuri, Upasana Sahu, Sara A. Murphy, Bangxing Hong, Ravindra Kolhe, Ashok Sharma, Balveen Kaur
Institutions: The University of Texas MD Anderson Cancer Center, Augusta University, The University of Texas Health Science Center at Houston
Language: English

Topic: Virus-based gene therapy research
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Cancer Institute, National Institute of Neurological Disorders and Stroke
Awards: Next Gen Virotherapy for GBM, Next generation oncolytic virotherapy targeting AKT and ERK signaling in glioma, Circumventing Barriers to Effective Oncolytic Virotherapy of Malignant Gliomas, Development of murine glioblastoma model for oncolytic HSV therapy
OpenAlex ID: W4417475420
FWCI: 0.533
Cites: 55
Cited by: 1
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