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Studies on the production and optimization of yellow pigment extracted from the SB2 strain and evaluation of its antioxidant properties

Year: 2025

Type: article

Abstract: Actinobacteria are filamentous bacteria that exist independently in soil, oceans, and the atmosphere, producing secondary metabolites with antioxidant and anti-cancer properties. Among these, the SB2 strain is a yellow-pigmented, gram-positive, coccus-shaped bacterium. Raman spectroscopy of SB2 cultures revealed a wave number (cm-1) of 1382.47, which indicates pigment production and was further supported by UV-Vis spectral analysis at 450 nm that confirmed the presence of carotenoid pigment in methanolic extracts of SB2. For optimal pigment synthesis, SB2 required a pH of 7, a temperature of 30 °C, and a nutritional medium with 1% molasses, 1.2% olive oil, and 1% peptone. The yellow pigment extracted from SB2 (500 μg ml-1) demonstrated DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging activity.

Source: German Journal of Pharmaceuticals and Biomaterials

DOI: 10.5530/gjpb.2025.3.8

Authors: Sandanakirouchenane Aroumougame, Kottakota Chandrasekhar, Douglas J H Shyu

Institutions: Pondicherry University, Sri Krishnadevaraya University, National Pingtung University of Science and Technology

Language: English

Topic: Microbial Metabolism and Applications

Subfield: Biotechnology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: diamond

OpenAlex ID: W4417482852

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