Work

The pivotal role of endoplasmic reticulum in cancer glucose metabolism

Year: 2025

Type: article

Abstract: silencing) and hydrolysis (by silencing glucose-6-phosphatase) eventually results in a measurable ER collapse documenting the high-rate nature of G6P flux across the reticular membrane.

Source: iScience

DOI: 10.1016/j.isci.2025.114503

Authors: Cecilia Marini, Maddalena Ghelardoni, Sonia Carta, Tiziana Bachetti, Silvia Bruno, Isotta Cainero, Silvia Ravera, Roberto Benelli, Marco Scotto, Francesca Vitale, Santina Bruzzone, Serena Losacco, Sabrina Chiesa, Matteo Bauckneht, Gabriele Tancreda, Matteo Raineri, Anna Maria Orengo, Andrea Benzi, Gianmario Sambuceti

Institutions: Ospedale Policlinico San Martino, National Research Council, University of Genoa, Italian Institute of Technology

Language: English

Topic: Cancer, Hypoxia, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,240

Funders: Ministero della Salute, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale"

OpenAlex ID: W4417488649

FWCI: 0.327

Cites: 47

Cited by: 1

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