Work

Systematic review and meta-analysis of placebo cure in onychomycosis clinical trials

Year: 2025

Type: review

Study designs: Systematic Review, Meta-Analysis

Abstract: There are effective treatments for onychomycosis. However, patients may defer treatment due to potential side effects of oral medications, the inconvenience of applying topical medications, or costs, and may inquire about resolution without treatment. Spontaneous resolution of onychomycosis is underexplored1 but is generally thought to be zero or minimal.2 Therefore, we conducted a systematic review and meta-analysis to assess the proportion of onychomycosis resolution among placebo-treated patients.

Source: JAAD reviews.

DOI: 10.1016/j.jdrv.2025.12.002

Authors: Julianne M. Falotico, Zachary J.K. Neubauer, Anjile An, Shari R. Lipner

Institutions: Stony Brook Medicine, Stony Brook University, Thomas Jefferson University, Weill Cornell Medicine

Language: English

Topic: Nail Diseases and Treatments

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,000