Work

Libman-Sacks endocarditis of the mitral valve as a first presentation of systemic lupus erythematosus

Year: 2025

Type: article

Abstract: Libman-Sacks endocarditis (LSE) is noninfectious verrucous vegetation lesion that can mimic infective endocarditis and the mitral valve is commonly involved. Although the exact pathogenesis remains unclear, the presence of LSE is associated with primary antiphospholipid syndrome (APS) and APS secondary to systemic lupus erythematosus (SLE). The presentation varies from mild symptoms to fulminant disease with high thromboembolic risk. Here, we present a case of LSE in female patient presented with shortness of breath and recurrent strokes but no clinical features of SLE. High index of suspicion remains a key factor in making the correct diagnosis.

Source: Journal of Surgical Case Reports

DOI: 10.1093/jscr/rjaf989

Authors: Nael Al-Sarraf, Samah AlKharji, Mohammed Hasan, Ali Alhumaidan

Institution: Adan Hospital

Language: English

Topic: Systemic Lupus Erythematosus Research

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,000