Work

Cerebellar hypoplasia in an Amur leopard cat (Prionailurus bengalensis euptilura) with feline panleukopenia virus infection

Year: 2025

Type: article

Abstract: ). Understanding the impact of such viral diseases on wild populations is crucial for advancing conservation efforts and protecting wildlife. An orphaned Amur leopard cat exhibiting idiopathic ataxia was rescued. Initial diagnostics, including physical examination, radiography, and blood analysis, yielded no remarkable findings, though its clinical signs indicated an underlying neurological problem. Subsequent real-time polymerase chain reaction tests detected FPV. Magnetic resonance imaging (MRI) revealed brain lesions, including reduced cerebellar parenchyma and cerebrospinal fluid occupying the space where the cerebellum should be located. These findings suggested cerebellar hypoplasia caused by in utero FPV infection. The Amur leopard cat was euthanised owing to its permanent disability, and the necropsy confirmed a markedly shrunken cerebellum. At the same time, histopathology identified decreased cellularity of the molecular and granular layers of the cerebellar cortex. These results coincided with the MRI findings. This report suggests that cerebellar hypoplasia caused by FPV can occur in wild felid species.

Source: Veterinární Medicína

DOI: 10.17221/29/2025-vetmed