Work

Tuning the efficiency of molecular probes via quinone methide-based in situ labeling

Year: 2025

Type: article

Abstract: In this work, we tuned quinone-methide based fluorescent probes containing different phenol linker modifications using two logical chemical approaches to improve probe stability, protein-fluorophore adduct yield, and cellular retention and contrast.

Source: RSC Chemical Biology

DOI: 10.1039/d5cb00138b

Authors: Zachary Rabinowitz, Seyedehalaleh Anvar, Jun Liu, Zixin Chen, Yuzhao Zhang, Chao Cui, Ashton Sigler, Lina Cui

Institutions: University of Florida, University of New Mexico

Language: English

Topic: Molecular Sensors and Ion Detection

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,962

Funders: University of Florida Health, National Institute on Aging, National Institute of General Medical Sciences

Awards: G2153269556, G4854955163, G6350848117, G6976140657

OpenAlex ID: W4417524827

FWCI: 0.738

Cites: 59

Cited by: 3

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