Unmasking the mimic: vertebral alveolar echinococcosis diagnosed by metagenomic next-generation sequencing
Year: 2025
Type: article
Study design: Case Report
Abstract: A Siberian woman in her forties presented to a public hospital in northeastern Germany with chronic back pain and a paravertebral mass, initially misdiagnosed as spinal tuberculosis. Repeated biopsies and metagenomic next-generation sequencing (mNGS) ultimately confirmed vertebral alveolar echinococcosis. Haplotype analysis revealed a novel Asian-cluster variant, supporting the presumed origin of infection.
Source: Infection
Authors: Tassilo Kruis, Marion Wassermann, Barbara Graf, Katharina Lührig, Peter Menzel, Rolf Schwarzer, Johannes Ziegler, Caroline Isner
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,790
OpenAlex ID: W4417530625