Work

Hair Graying Update and Review

Year: 2025

Type: article

Abstract: Graying is a natural process, characterized by the loss of pigment in the hair, and is considered a sign of aging in society; its onset and progression is closely correlated with age and occurs to varying degrees in all individuals, regardless of gender or race. However, premature graying has a psychological and social impact, affecting patients' self-esteem. The exact etiopathogenesis is still unknown, and it has been associated with multiple factors such as: oxidative stress, ultraviolet radiation, genetic factors, and lifestyle factors such as smoking, nutritional and emotional factors. All of this causes a decrease in the production of melanin by the melanocytes of the hair bulb. Despite the extensive molecular research being carried out to understand the pathogenesis of graying, there is a shortage of effective, evidence-based treatment options. Today, graying has become a cultural phenomenon, where many people opt for cosmetic treatments to cover gray hair.

Source: Actas Dermo-Sifiliográficas

DOI: 10.1016/j.ad.2025.104564

Authors: K.M. Ramirez-Gomez, A. Imbernon-Moya, M.F. Villegas-Calzada, S. Vano-Galvan, D. Saceda-Corralo

Institutions: Hospital Universitario Severo Ochoa, Universidad de Alcalá, Instituto Ramón y Cajal de Investigación Sanitaria, Hospital Universitario Ramón y Cajal

Language: English

Topic: Hair Growth and Disorders

Subfield: Urology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,080