Work

Chronic Intracerebral LPS as a Model of Neuroinflammation

Year: 2003

Type: book-chapter

Abstract: This chapter will describe our recent progress in studying the effects of chronic neuroinflammation in order to better understand the contribution of this condition to neuro-degeneration. The animal model to be discussed is directed at a better understanding of the role of chronic neuroinflammation in the progression of Alzheimer’s disease (AD). The most important point to make at the onset of this review is that we do not believe that neuroinflammation causes AD. Rather, this chapter will outline the details of an animal model that has provided compelling evidence that inflammation develops in response to existing genetically determined conditions within brains of AD patients.

Source: Humana Press eBooks

DOI: 10.1007/978-1-59259-297-5_6

Authors: Gary L. Wenk, Beatrice Hauss-Wegrzyniak

Language: English

Topic: Neuroinflammation and Neurodegeneration Mechanisms

Subfield: Neurology

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W47715159

FWCI: 3.794

Cites: 87

Cited by: 9

Related to: 10