Work

Genetic Alterations in Prostatic Intraepithelial Neoplasia (PIN)

Year: 2001

Type: book-chapter

Abstract: Prostatic intraepithelial neoplasia (PIN) is the histologic lesion most strongly associated with prostate cancer, and has been postulated to be a premalignant lesion. However, much of the natural history of PIN remains unknown. A more fundamental understanding of the relationship between PIN and invasive tumors at the molecular level is critically needed, and represents an important future challenge for investigators. This chapter reviews the clinical, pathologic, and genetic studies addressing the relationship between PIN and cancer. The final section presents newly developing techniques and research approaches in molecular pathology and describes how these methods can be used to study PIN.

Source: Prostate Cancer

DOI: 10.1007/978-1-59259-009-4_9

Authors: Paul H. Duray, David K. Ornstein, Cathy D. Vocke, Stephen M. Hewitt, Kristina A. Cole, John W. Gillespie, Chad R. Englert, Emanuel F. Petricoin, David B. Krizman, W. Marston Linehan, Michael R. Emmert-Buck

Language: English

Topic: Prostate Cancer Treatment and Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $1,000

OpenAlex ID: W50853546

FWCI:

Cites: 105

Cited by: 1

Related to: 10