Effect of Thermal Acclimation on Blood Pressure and Stress-induced Elevation of Core Temperature in Spontaneously Hypertensive Rats and Wistar Rats
Year: 1992
Type: article
Abstract: : Male adult rats of the three strains, spontaneously hypertensive rats (SHR), Wistar-Kyoto rats (WKY) and Wistar rats (WIS) were used. Rats of each strain, at 1 month old, were randomly divided into three groups and chronically exposed to 3 different cuff method and stress-induced elevation of core temperature were compared. In cold-ac-climated WKY and WIS, BP was significantly higher than that in the heat-acclimated rat. In SHR, genetically hypertensive rats, there was no significant difference in BP between cold- and heat-acclimated young adult rats, and BP in heat-acclimated older adult rats was higher than that in cold-acclimated SHR. In normotensive rats, WKY and WIS, thermal ac-climation affected systemic BP. In normotensive strains, WKY and WIS, cold-acclimation in-creased BP, whereas heat-acclimation decreased BP. Mean body weights in cold-acclimated rats were greater than those of heat-acclimated ones in all strains except for older adult WKY.For restraint stress, the conscious rat was paced in a loosely fitting small cage. Cold was no significant difference among the rectal temperatures of these four groups. During the restraint stress, elevated core temperature was sustained and tail skin temperature decreased. Both values of rectal temperature (Tre) at the 30th min and increase of Tre
Authors: Katsuhiko Tsuchiya, Mitsuo Kosaka
Language: English
Subfield: Physiology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W54403775