Cytokine activity in bovine mammary gland secretions during the periparturient period.
Year: 1991
Type: article
Abstract: The presence of cytokine activity in periparturient bovine mammary secretions was evaluated. Mammary secretions were modified for use in biological assays for interleukin-2 (IL-2) like and antiviral activity. The level of IL-2 like activity in mammary gland secretions was lower during the last week of gestation when compared to levels detected approximately two weeks prepartum. Antiviral titers gradually increased as parturition approached. Results from Western blots indicated that the antiviral activity observed in prepartum secretions may be due to tumor necrosis factor (TNF). Interferons (IFN) were not detected in the colostrum samples.
Source: Europe PMC (PubMed Central)
Authors: L M Sordillo, M J Redmond, M Campos, L Warren, L A Babiuk
Institution: University of Saskatchewan
Language: English
Subfield: Animal Science and Zoology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W56643777