Liposomes in thrombolytic therapy : t-PA targeting with plasminogen-liposomes, a novel concept
Year: 1995
Type: dissertation
Abstract: Chapter 1General introduction Chapter 2a Development of a procedure for coupling the homing device glu-plasminogen to liposomes 19 Chapter 2b Interference of e-amino-caproic acid with [N-Succinimidyl S-acetylthioacetate derived] thiol introduction into glu-plasminogen 37 Chapter 3 Fibrin binding of glu-plasminogen coated liposomes in vitro 47 Chapter 4 The preparation of tissue-type Plasminogen Activator (t-PA) containing liposomes: entrapment efficiency and ultracentrifugation damage 65 Chapter 5 Long term stability of liposomes containing both enzyme and its substrate: the challenge to formulate stable liposomes containing both tissue-type Plasminogen Activator & glu-plasminogen 83 Chapter 6 Thrombolytic treatment with tissue-type Plasminogen Activator (t-PA) containing liposomes in rabbits: a comparison with free t-PA 101 Chapter 7 Final considerations and prospects / results of ongoing research
Source: TNO Repository
Author: J.L.M. Heeremans
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W568345622