Angiogenic activity of human villi and decidua in the first trimester of pregnancy.
Year: 1994
Type: article
Abstract: Angiogenic activity in the extracts of human villi and decidua in the first trimester of pregnancy was examined using chorioallantoic membrance assay. Blood vessel density on the chorioallantoic membrane increased greatly with the addition of villi extract, and slightly by decidua extract. Neovascularization with a spoke wheel appearance was induced by both villi and decidua, and this response pattern by the villi was stronger than that by the decidua. Maternal serum did not induce any vascular response. These results suggested that angiogenic activity was present both in the villi and decidua in the first trimester of pregnancy and that the villi activity was stronger than the decidua.
Source: PubMed
DOI: 10.15017/7329772
Authors: Y Onoyama, H Shimokawa, K Sakai, N Honda, H Nakano
Institution: Kyushu University
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W578927127