Evidence for the similar biochemical background for psychiatric disorders and psychoactive substances addiction
Year: 2014
Type: article
Abstract: Nowadays, the effects of psychoactive substances dependence are becoming more severe and acute on the social level, so this topic of research appears in the orbit of interest to many subdisciplines, such as psychiatry, neuropsychology, neurosciences and biochemistry. The authors conducted a literature review devoted to psychiatric disorder and addiction to alcohol and other psychoactive substances in order to present evidence for the similar biochemical and neurophysiologic background for both of the mentioned above disorders. In this paper there are presented data of animal models, neuroimaging techniques and neuropsychological tests. Moreover, the authors of this paper try to identify the possible link between personality traits (e.g. impulsivity or novelty seeking) or inborn properties of the central nervous system and the development of addiction that can gradually lead to irreversible brain changes. The authors also address the phenomena of self-medication among schizophrenic patients using regularly tobacco. In the article there is also discussed the potential application of psychostimulants in the treatment of disorders such as Attention Deficit Hyperactivity Disorder (ADHD) or narcolepsy.
Source: Current Problems of Psychiatry
Language: English
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W586061846