Work

Antiarrhythmic therapy in atrial fibrillation: indications, guidelines, and safety.

Year: 2012

Type: article

Abstract: Antiarrhythmic agents work by blocking the sodium channel, the potassium channel, the calcium channel, or the adrenergic receptors. Sodium channel blockade reduces the rate of rise of phase 0, which prolongs the QRS complex. Potassium channel blockade, on the other hand, lengthens the repolarization (phase 4) and therefore prolongs the QT interval.1 Vaughan Williams Classification of Antiarrhythmic Drugs. In the Vaughan Williams classification system, class I agents are sodium channel blockers, class II are β-blockers, class III are potassium channel blockers, and class IV are calcium channel blockers.2

Source: PubMed

Authors: Armin Barekatain, Mehdi Razavi

Institution: The University of Texas Health Science Center at Houston

Language: English

Topic: Atrial Fibrillation Management and Outcomes

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W59706883

FWCI:

Cites: 11

Cited by: 8

Related to: 20