Work

A mathematical model for a comprehensive approach to the dynamics of human colonic aberrant crypt foci

Year: 2008

Type: preprint

Abstract: In this paper, we propose mathematical models for the growth dynamics \nof aberrant crypt foci in the human colon, as well as for some of their \ncharacteristics, namely the apoptosis and proliferation indices. The models rely on \nlogistic type differential equations and clinical observations at different times, and \ncan arguably be used as an auxiliary screening tool for colon cancer. We report \nseveral results using available medical data.

Source: Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)

Authors: Isabel N. Figueiredo, Pedro Figueiredo, Carlos Leal, José Miguel Urbano

Language: English

Topic: Mathematical Biology Tumor Growth

Subfield: Modeling and Simulation

Field: Mathematics

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W618610559

Cites: 33

Cited by:

Related to: 10