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SLOW FIBER-RICH PLANTARIS MUSCLE ABUNDANTLY EXPRESSES mRNA FOR MCIP1 IN RATS

Year: 2003
Type: article
Abstract: Mammalian skeletal muscles contain slow (type I) and fast (type II) muscle fibers in various ratios. The slow fiber has higher ability in oxidative phosphorylation compared to the fast fiber, and its preservation and maintenance are important for physical exercise and health promotion. Recently, the calcineurin signaling pathway has been reported to induce fast-to-slow muscle fiber conversion in rodents by activating the expression of slow fiber-specific genes (Fig. 1). However, it remains elusive whether genes in the calcineurin signaling pathway are differently expressed in the slow and fast fibers. To address this question, we investigated the expression of genes involved in this pathway of slow fiber-rich plantaris muscle, in addition to fast fiber-rich gastrocnemius and
Source: 体力科學
Language: English
Open Access status: diamond
OpenAlex ID: W619524919
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