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Vascular dementia: pharmacological treatment approaches and perspectives.

Year: 2007

Type: article

Abstract: Vascular dementia is a common condition for which there are no effective approved pharmacological treatments available. Absence of effective treatments creates a difficult situation for those suffering from the disease, their caregivers, and healthcare providers. This review will address our current understanding of the mechanisms of nerve cell damage due to ischemia and summarize available clinical trial data on several commonly used compounds including memantine, donepezil, galantamine, rivastigmine, nimodipine, hydergine, nicergoline, CDP-choline, folic acid, as well as such nonpharmacological approaches as validation therapy.

Source: PubMed Central

Authors: Andrius Baskys, Anthony C Hou

Institutions: University of California, Irvine, United States Department of Veterans Affairs

Language: English

Topic: Neurological Disease Mechanisms and Treatments

Subfield: Neurology

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W65830589

FWCI: 2.006

Cites: 47

Cited by: 94

Related to: 10