Work

Effects of ketamine on the developing central nervous system.

Year: 2007

Type: article

Abstract: Ketamine is a widely used drug in pediatric anesthesia practice, acting primarily through the blockade of the N-methyl-D-aspartate (NMDA) type of glutamate receptors. A growing body of laboratory evidence, accumulated during the past few years, suggests that this drug could have potential adverse effects on the developing central nervous system. The goal of this short review is to give a brief synopsis of experimental work indicating ketamine-induced developmental neurotoxicity as well as to discuss potential limitations concerning extrapolation of these studies to clinical practice.

Source: PubMed

Authors: László Vutskits, Eduardo Gascon, József Zoltán Kiss

Institutions: University Hospital of Geneva, University of Geneva, Semmelweis University

Language: English

Topic: Anesthesia and Neurotoxicity Research

Subfield: Developmental Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6745079

FWCI: 0.096

Cites: 45

Cited by: 11

Related to: 10