Development and evaluation of a study design typology for human research.
Year: 2009
Type: article
Abstract: A systematic classification of study designs would be useful for researchers, systematic reviewers, readers, and research administrators, among others. As part of the Human Studies Database Project, we developed the Study Design Typology to standardize the classification of study designs in human research. We then performed a multiple observer masked evaluation of active research protocols in four institutions according to a standardized protocol. Thirty-five protocols were classified by three reviewers each into one of nine high-level study designs for interventional and observational research (e.g., N-of-1, Parallel Group, Case Crossover). Rater classification agreement was moderately high for the 35 protocols (Fleiss' kappa = 0.442) and higher still for the 23 quantitative studies (Fleiss' kappa = 0.463). We conclude that our typology shows initial promise for reliably distinguishing study design types for quantitative human research.
Source: Europe PMC (PubMed Central)
Language: English
Subfield: Statistics, Probability and Uncertainty
Field: Decision Sciences
Domain: Social Sciences
Open Access status: green
Awards: Clinical and Translational Science Institute, Institute for Clinical and Translational Research (UL1), Transforming Translational Science and Education to Benefit Human Health, UC Davis Clinical and Translational Science Center, North and Central Texas Clinical and Translational Science Initiative (UL1), Institute for Integration of Medicine & Science: A Partnership to Improve Health, Institute for Integration of Medicine & Science: A Partnership to Improve Health, Duke CTSI, Ontology-Based Integration of Human Studies Data
OpenAlex ID: W68494008