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Current status and prospects of immunotherapy for locally advanced nasopharyngeal carcinoma

Year: 2024

Type: article

Abstract: Nasopharyngeal carcinoma (NPC) is a squamous cell carcinoma arising from the nasopharyngeal epithelium, which is associated with Epstein-Barr virus (EBV) infection and is most common in southern China. Immunotherapy, particularly immune checkpoint inhibitors (ICIs), provides favorable efficacy with a good safety profile in a variety of solid tumors, including recurrent or metastatic NPC (R/M-NPC). In addition, immunotherapy has made new breakthroughs in the treatment of locally advanced NPC, and many clinical studies are underway. Based on previously reported results, this study presents a comprehensive overview of the advances and challenges by introducing the basic principles and the current status of immunotherapy in NPC, with the expectation that it will serve as a reference for clinical practice in the future.

Source: DOAJ (DOAJ: Directory of Open Access Journals)

DOI: 10.16190/j.cnki.45-1211/r.2024.09.009

Authors: LIU Xixi, SUN Yajie, YANG Kunyu

Institutions: Wuhan Union Hospital, Huazhong University of Science and Technology

Language: English

Topic: Head and Neck Cancer Studies

Subfield: Otorhinolaryngology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6887484565

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