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Analyzing the Feasibility of Surgical Approaches to Improve Cerebral Lymphatic Circulation in Alzheimer Disease

Year: 2024

Type: article

Abstract: Traditionally, it was believed that the human brain lacked lymphatic vessels. However, recent studies have progressively confirmed the existence of meningeal lymphatic vessels and the glymphatic system. Alzheimer disease (AD) is a neurodegenerative disorder, and brain lymphatic circulatory dysfunction may contribute to its development. This article reviews the current status and challenges of treating AD through the brain lymphatic system, examining the relationship between circulatory disorders and AD. Additionally, it explores the feasibility of enhancing lymphatic circulation through deep cervical lymphaticovenular anastomosis as a potential treatment for AD, providing a valuable reference for future therapeutic strategies.

Source: DOAJ (DOAJ: Directory of Open Access Journals)

DOI: 10.3969/j.issn.1674-7593.2024.06.016

Authors: Zhao Yangguang, Li Xia, Fang Yuan, Zhang Yonghong, Ren Zhenhu

Institutions: Henan University, Henan University Huaihe Hospital and Huaihe Clinical Institute, Shanghai Mental Health Center

Language: English

Topic: Cerebrospinal fluid and hydrocephalus

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6891556926

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