Marked Hemoglobin Mass Expansion and Plasma Volume Contraction in Sherpas Acclimatizing to 5,400 m Altitude
Year: 2024
Type: article
Abstract: We measured the hematological response to ∼6 wk exposure to an altitude of 5,400 m in Sherpa highland natives and Nepalese lowlanders. While the increase in hemoglobin concentration at high altitudes tended to be smaller in Sherpas than in lowlanders, the two groups experienced a similar reduction in plasma volume and increase in hemoglobin mass. We conclude that the hematological response of Sherpas to high-altitude exposure does not fundamentally differ from that of lowlanders.
DOI: 10.5167/uzh-266506
Authors: Roche, Johanna, Baniya, Santosh, Bhatta, Suraj, Subedi, Sachin, Gatterer, Hannes, Rasmussen, Peter, Hilty, Matthias Peter, Sigg, Anne-Aylin, Timalsina, Santosh, Siebenmann, Christoph
Language: English
Topic: High Altitude and Hypoxia
Subfield: Genetics
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W6892251376
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