The Relevance of Secretor Status perspectives in individuals
Year: 2024
Type: article
Abstract: Those that release blood group antigens in their tears, perspiration, saliva, semen, and serum are said to have secretor status. People who do not release their blood group antigens into their bodily fluids are known as nonsecretors. One's vulnerability to certain diseases and infections is increased when blood type antigens are absent from bodily fluids. The risk of developing bacterial and viral infections, cancerous and precancerous oral disorders, chronic periodontitis, autoimmune diseases, diabetes, heart disease, and dental caries is higher in nonsecretors. The secretor gene produces the enzyme fucosyltransferase 2. The sugar moiety of glycolipids and glycoproteins is enhanced by this enzyme with fucose. H is created in secretions by fucosyltransferase 2 on precursor oligosaccharides chain (type A). Fucosyltransferase 3 can produce Le/b by incorporating fucose into H. Therefore, everyone with a Le/b phenotype is a secretor. Fucosylated oligosaccharides are present on the surface of cells and are involved in a number of important biological processes, including adhesion, motility, and differentiation. Compared to non-secretors, ABH secretors' saliva and other bodily secretions include a significant amount of carbohydrates.
Authors: Kanu S.N., Nnodim A.P., Johnkennedy N
Institution: Imo State University
Language: English
Topic: Blood groups and transfusion
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W6893009131
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