Work

In Pursuit of Precision: Investing oxygen impact on breast cancer spheroids

Year: 2024

Type: article

Abstract: This study focuses on the effects of oxygen levels on MDA-MB-231 breast cancer spheroids. By comparing spheroid growth in hyperoxic (18.5% O₂) and hypoxic (2% O₂) environments using advanced 3D cell culture techniques, the research highlights significant differences in cell growth, structure, and metabolism. The findings suggest that mimicking in vivo oxygen levels is crucial for more accurate disease modeling.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.13837438

Authors: Charelt-Faure, Claire, Rogowska-Wrzesinska, Adelina, Wrzesinski, Krzysztof

Institution: University of Southern Denmark

Language: English

Topic: Cancer, Hypoxia, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6893033356

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