Work

Pioglitazone Matrix Patches: In Vitro Methodologies And Efficacy Assessment - A Review

Year: 2024

Type: article

Abstract: Pioglitazone, an oral antidiabetic drug, has limited bioavailability due to extensive first-pass metabolism. Matrix-type transdermal patches offer a promising alternative for drug delivery. This review aims to provide a comprehensive overview of in-vitro studies, methodologies, and assessments of matrix-type transdermal patches containing pioglitazone. We discuss the formulation development, characterization, and evaluation of these patches, including in-vitro release, permeation, and skin irritation studies. The review also highlights the advantages and challenges of using pioglitazone in transdermal patches and identifies areas for future research. Our comprehensive analysis provides valuable insights for researchers and formulation scientists working on transdermal drug delivery systems, particularly for pioglitazone.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.13955575

Author: Ningaraj Arer*1, Hanamant B. Sannakki2, Vishwanath Halappanavar2, Shridhar Gaikwad3, Adarsh Utale4

Language: English

Topic: Advancements in Transdermal Drug Delivery

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6893040912

FWCI:

Cites:

Cited by:

Related to: